Bactrim (Co-trimoxazole), an antibacterial combination drug, is prescribed for the treatment of certain urinary tract infections, severe middle ear infections in children, long-lasting or frequently recurring bronchitis in adults that has increased in seriousness, inflammation of the intestine due to a severe bacterial infection, and travelers' diarrhea in adults. Bactrim is the fixed-dose preparation of trimethoprim (80mg) plus sulphamethoxazole (400mg). Co-trimoxazole acts by inhibiting bacterial protein synthesis. Bactrim is also prescribed for the treatment of Pneumocystis carinii pneumonia, and for prevention of this type of pneumonia in people with weakened immune systems.
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The usual adult dosage in the treatment of urinary tract infection is 1 DS (double strength tablet) or 2 tablets every 12 hours for 10 to 14 days. The dosage for inflammation of the intestine is the same but is taken for 5 days. The recommended dosage for the treatment of Pneumocystis Carinii Pneumonia is 15 to 20 mg of trimethoprim and 75 to 100 mg of sulfamethoxazole per 2.2 pounds of body weight per 24 hours divided into equal doses every 6 hours for 14 to 21 days. The usual recommended dosage for Travelers' diarrhea is 1 DS (double strength tablet) or 2 tablets, or 4 teaspoonfuls (20 ml) of Bactrim pediatric suspension every 12 hours for 5 days.
Stop taking the drug and seek emergency medical attention if you experience any of the following serious side effects: an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives); unusual bleeding or bruising; or yellow skin or eyes. Continue to take your medication and talk to your doctor if you experience headache, fatigue, or dizziness; nausea, vomiting, decreased appetite, or diarrhea; weakness; or increased sensitivity to the sun.